Part Ⅰ PRINCIPLES OF MOLECULAR CARDIOLOGY
1 General Pringciples of Molecular Biology
2 Genetic Approaches to Cardiovascular Disease
3 Genetically Modified Animal Models in Cardiovascular Pesearch
4 Gene Transfer Approaches for Cardiovascular Disease
Part Ⅱ MORPHOGENESIS AND CARDIOVASCULAR DISEASES
5 Molecular Advances in Cardiovascular Development
6 Molecular Genetics of Congenital Heart Disease
7 Inherited Vascular Disease
Part Ⅲ CARDIAC MUSCLE AND MYOPATHIES
8 Structure and Funciton Relationships in Contractile
9 Molecular and Cellular Biology of Cardiac Hypertrophy and Failure
10 Molecular Genetics of Inherited Cardiomyopathies
11 Mitochondrial Genes in Myopathy,Cardiomyopathy,and Stroke
Part Ⅳ CARDIAC CONDUCTION AND ARRHYTHMIAS
12 Normal Cardiac Electrophysiology
13 Molecular Basis of Inherited Cardiac Arrhythmias
14 Molecular Approaches to Arrhythmogenesis
Part Ⅴ VASCULAR BIOLOGY AND ATHEROGENESIS
15 Biology of the Vessel Wall:Endothelium
16 Atherogenesis and Inflammation
17 Restenosis Injury:A Problem in Regulation of Growth
18 Angiogenesis in Cardiovascular Disease
Part Ⅵ RISK FACTORS FOR CORONARY ARTERY DISEASE
19 Disorders of Lipoprotein Metabolism
20 Lipoprotein Receptors and Cellular Cholesterol Metabolism in Health and Disease
21 Lipoprteins,Lipoprotein Oxidation,and Atherogenesis
22 Molecular Genetics of Non-Insulin Dependent Diabetes Mellitus
Part Ⅶ MOIECULAR BASIS OF HEMOSTASIS DISORDERS
23 Blood Coagulation in Cardiovascular Disease
24 The Fibrinolytic System and Thrombolytic Therapy
25 Platelet Thrombus Formation and Antiplatelet Therapy
Part Ⅷ GLOSSARY OF MOLECULAR GENETICS
Index
The very substantial advances in the diagnosis and management of patients with cardiovascular dis-eases represent one of the medical triumphs of the twentieth century. These great strides have been based on solid foundations of cardiovascular physi-ology and pharmacology and in many instances on the clinical applications of bioengineering. Notable examples include the development of a variety of accurate invasive and noninvasive diagnostic tech-niques and several classes of drugs that have pro-foundly beneficial effects on patients with cardio-vascular disease, as well as open heart surgery,percutaneous catheter-based coronary revasculari-zation, artificial cardiac valves, cardiac pacemakers,and internal cardioverter-defibrillators. These have prolonged and improved the quality of the lives of millions of individuals worldwide.
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